DMSO (Dimethyl Sulfoxide)
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DMSO (Dimethyl Sulfoxide) | Versatile Solvent for Advanced Formulations
Discover the versatility of DMSO (Dimethyl Sulfoxide), a highly polar, water-miscible organic solvent valued for its exceptional dissolving capabilities and specialized applications in cosmetic research, laboratory work, and advanced formulation development.
Known for its ability to dissolve a wide range of organic and inorganic substances, DMSO offers formulators a unique tool for working with ingredients that may be difficult to incorporate into conventional solvent systems.
Key Features & Benefits
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Exceptional Solvent Properties: A highly polar aprotic solvent capable of dissolving many compounds with varying chemical characteristics.
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Water-Miscible: Blends completely with water, providing flexibility in solvent-system development.
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Specialized Formulation Versatility: Useful for laboratory research, ingredient solubility testing, and technical formulation development.
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Penetration-Enhancing Properties: Known to increase the movement of certain substances across biological membranes, a characteristic requiring careful safety evaluation.
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Low Volatility: Its relatively high boiling point makes DMSO useful in applications requiring a less volatile solvent.
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Multi-Purpose Ingredient: Suitable for a variety of research, laboratory, and industrial formulation processes.
Common Applications
Cosmetic Ingredient Research
Used in controlled laboratory settings to investigate ingredient solubility, compatibility, and formulation behavior.
Solvent & Co-Solvent Systems
Useful for dissolving selected compounds that may exhibit limited solubility in water or other conventional solvents.
Research & Development
A widely studied solvent in chemical research, analytical testing, and experimental formulation development.
Specialized Technical Applications
Used in laboratory processes and other industrial applications where its distinctive solvent characteristics are beneficial.
Formulation Guidelines
DMSO requires special consideration due to its strong solvent activity and ability to enhance the absorption of certain substances through the skin.
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Recommended Use Level: Application-dependent; no universal cosmetic usage percentage is recommended.
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Solubility: Completely miscible with water and compatible with many organic solvents.
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Incorporation: May be incorporated into appropriately designed solvent systems following compatibility and stability testing.
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Compatibility: Evaluate all ingredients, processing equipment, packaging materials, and potential contaminants before use.
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Formulation Testing: Conduct appropriate stability, compatibility, toxicological, and regulatory assessments before incorporating DMSO into any finished product.
Important: DMSO can increase dermal absorption of other substances, including unwanted contaminants. It should not be incorporated into consumer-applied topical products without a qualified safety assessment of the complete formulation.
Product Specifications
INCI: dimethyl sulfoxide
CAS Number:67-68-5
Appearance: Achromatic or yellowish Liquid
Solubility: Completely miscible with water, ethanol and most common organic solvents
Usage Rate: Application-dependent; 0.5–10% for cosmetic applications, used as a co‑solvent and penetration enhancer. Higher loading increases potential skin irritation. Local regulatory compliance should be confirmed prior to formulation.
Ingredient Function: Solvent
Shelf Life & Storage
Store tightly sealed in a cool, dry, well-ventilated area, protected from moisture, incompatible substances, and excessive heat.
DMSO is hygroscopic, meaning it readily absorbs moisture from its surroundings. Keep containers closed when not in use and use packaging materials verified for chemical compatibility.
Cold Weather Notice: DMSO may crystallize or solidify at temperatures below approximately 65°F (18.5°C). This is a normal physical characteristic of the ingredient and does not necessarily indicate a quality issue. Allow the sealed container to return gradually to a suitable temperature before use.
Shelf Life: Refer to the manufacturer's recommended expiration or retest date and the product's batch documentation.
Safety & Handling
For laboratory, research, and appropriate technical formulation use only.
DMSO is not intended for ingestion, injection, self-treatment, or direct application to the skin as supplied. Avoid contact with skin and eyes, use appropriate protective equipment, and follow the product's Safety Data Sheet (SDS).
Because DMSO can enhance the absorption of other chemicals through the skin, special precautions are necessary when handling it alongside other substances.
This product is not marketed as a drug or for the diagnosis, treatment, cure, or prevention of any disease.
Documents
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