Coenzyme (NAD+) Nicotinamide Adenine Dinucleotide
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NAD+ (Nicotinamide Adenine Dinucleotide)
NAD+ (Nicotinamide Adenine Dinucleotide) is a naturally occurring coenzyme found in every living cell and is essential for cellular energy production, DNA repair, and healthy skin function. Widely recognized in advanced skincare, NAD+ helps support the skin’s natural renewal processes while promoting a more radiant, resilient, and youthful-looking complexion.
As a key player in cellular metabolism, NAD+ assists enzymes involved in energy production (ATP) and repair mechanisms that help defend skin against environmental stressors and oxidative damage. It is commonly incorporated into premium anti-aging formulations, brightening serums, and skin recovery treatments.
NAD+ is highly sensitive to heat, alkaline pH, and prolonged exposure to light. For best results, formulate at cool temperatures and store finished products in airtight, opaque packaging.
Ideal For
- Anti-aging serums
- Brightening treatments
- Skin recovery formulations
- Barrier support products
- Premium facial creams and gels
Product Information
INCI: Nicotinamide Adenine Dinucleotide
Appearance: White crystalline powder
Solubility: Water soluble
Recommended Usage Rate: 0.5–1%
Formulation notes: Vortex mixing is recommended to fully dissolve. Use of a sonicator may also be necessary. NAD+ degrades rapidly with heat (38C and up) and alkaline pH. We recommend storing your finished formulations in the refrigerator for maximum potency.
Storage:
Store tightly sealed in a cool, dry location away from heat, moisture, and direct light. Refrigeration is recommended after opening.
Shelf Life: 24 months
Works Well With
NAD+ pairs exceptionally well with many advanced cosmetic actives, including:
- Niacinamide – Supports the skin barrier while complementing NAD+’s role in cellular energy.
- PDRN – Excellent for skin renewal and recovery formulations.
- GHK-Cu Peptide – Helps create premium rejuvenating serums.
- Acetyl Hexapeptide-8 (Argireline® alternative) – Targets the appearance of expression lines.
- Ectoin – Provides hydration and environmental stress protection.
- Panthenol (Vitamin B5) – Adds soothing and moisture support.
- Sodium Hyaluronate (Hyaluronic Acid) – Delivers long-lasting hydration.
- Coenzyme Q10 – Powerful antioxidant support for mature skin.
- R-Alpha Lipoic Acid – Creates an advanced antioxidant complex.
- Vitamin C Derivatives – Brightening and antioxidant support when formulated for compatibility.
Product Inspiration
NAD+ is an excellent ingredient for creating:
- Luxury Cellular Renewal Serum
- Overnight Recovery Elixir
- Age-Defying Peptide Serum
- Brightening Repair Essence
- DNA Defense Facial Gel
- Advanced Eye Renewal Serum
- Premium Bio-Energy Moisturizer
- Professional Post-Treatment Recovery Serum
- Skin Longevity Cream
- Antioxidant Power Concentrate
This ingredient is particularly well suited for high-end formulations designed to support healthy-looking, energized skin and pairs beautifully with the peptide, PDRN, ectoin, and antioxidant ingredients you’re already carrying in the Ingredient Collective lineup.
NAD+ is a coenzyme that provides anti-aging and skin health benefits similar to niacinamide. a form of vitamin B-3. Adequate NAD+ levels are critical for proper DNA repair upon UV exposure. NAD+ deficiency increases skin sensitivity to photodamage, whereas NAM prevents UV-induced depletion of cellular energy by replenishing the NAD+ pool.
Nicotinamide adenine dinucleotide (NAD+) is crucial to life. It works as an electron/hydrogen carrier that facilitates the transfer of energy between nutrients and the cell’s energy currency, ATP. In these oxidation-reduction reactions, the active part of the coenzyme (the one that gets reduced and oxidized again and again) is nicotinamide. NAD+ is non-organic.
Suggested Use & Storage
All products sold are cosmetic grade; External Use Only; Cosmetic & Personal Care Formulations Only.
This product should be added to a formulation at the recommended usage rate.
Documents
SDS
CoA-LOT: BN250330/CA
CoA-LOT: BN260728/CA
CoA-LOT: BN260509/CA
CoA-LOT: BN20230916/CA
CoA-LOT: BN221204/CA
CoA-LOT: BN240830/CA
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