Coenzyme (NAD+) Nicotinamide Adenine Dinucleotide

Coenzyme (NAD+) Nicotinamide Adenine Dinucleotide

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NAD+ (Nicotinamide Adenine Dinucleotide)

NAD+ (Nicotinamide Adenine Dinucleotide) is a naturally occurring coenzyme found in every living cell and is essential for cellular energy production, DNA repair, and healthy skin function. Widely recognized in advanced skincare, NAD+ helps support the skin’s natural renewal processes while promoting a more radiant, resilient, and youthful-looking complexion.

As a key player in cellular metabolism, NAD+ assists enzymes involved in energy production (ATP) and repair mechanisms that help defend skin against environmental stressors and oxidative damage. It is commonly incorporated into premium anti-aging formulations, brightening serums, and skin recovery treatments.

NAD+ is highly sensitive to heat, alkaline pH, and prolonged exposure to light. For best results, formulate at cool temperatures and store finished products in airtight, opaque packaging.

Ideal For

  • Anti-aging serums
  • Brightening treatments
  • Skin recovery formulations
  • Barrier support products
  • Premium facial creams and gels

Product Information

INCI: Nicotinamide Adenine Dinucleotide

Appearance: White crystalline powder

Solubility: Water soluble

Recommended Usage Rate: 0.5–1%

Formulation notes: Vortex mixing is recommended to fully dissolve.  Use of a sonicator may also be necessary. NAD+ degrades rapidly with heat (38C and up) and alkaline pH. We recommend storing your finished formulations in the refrigerator for maximum potency.

Storage:
Store tightly sealed in a cool, dry location away from heat, moisture, and direct light. Refrigeration is recommended after opening.

Shelf Life: 24 months

Works Well With

NAD+ pairs exceptionally well with many advanced cosmetic actives, including:

  • Niacinamide – Supports the skin barrier while complementing NAD+’s role in cellular energy.
  • PDRN – Excellent for skin renewal and recovery formulations.
  • GHK-Cu Peptide – Helps create premium rejuvenating serums.
  • Acetyl Hexapeptide-8 (Argireline® alternative) – Targets the appearance of expression lines.
  • Ectoin – Provides hydration and environmental stress protection.
  • Panthenol (Vitamin B5) – Adds soothing and moisture support.
  • Sodium Hyaluronate (Hyaluronic Acid) – Delivers long-lasting hydration.
  • Coenzyme Q10 – Powerful antioxidant support for mature skin.
  • R-Alpha Lipoic Acid – Creates an advanced antioxidant complex.
  • Vitamin C Derivatives – Brightening and antioxidant support when formulated for compatibility.

Product Inspiration

NAD+ is an excellent ingredient for creating:

  • Luxury Cellular Renewal Serum
  • Overnight Recovery Elixir
  • Age-Defying Peptide Serum
  • Brightening Repair Essence
  • DNA Defense Facial Gel
  • Advanced Eye Renewal Serum
  • Premium Bio-Energy Moisturizer
  • Professional Post-Treatment Recovery Serum
  • Skin Longevity Cream
  • Antioxidant Power Concentrate

This ingredient is particularly well suited for high-end formulations designed to support healthy-looking, energized skin and pairs beautifully with the peptide, PDRN, ectoin, and antioxidant ingredients you’re already carrying in the Ingredient Collective lineup.

NAD+ is a coenzyme that provides anti-aging and skin health benefits similar to niacinamide. a form of vitamin B-3.  Adequate NAD+ levels are critical for proper DNA repair upon UV exposure. NAD+ deficiency increases skin sensitivity to photodamage, whereas NAM prevents UV-induced depletion of cellular energy by replenishing the NAD+ pool.

Nicotinamide adenine dinucleotide (NAD+) is crucial to life. It works as an electron/hydrogen carrier that facilitates the transfer of energy between nutrients and the cell’s energy currency, ATP. In these oxidation-reduction reactions, the active part of the coenzyme (the one that gets reduced and oxidized again and again) is nicotinamide.  NAD+ is non-organic.

Suggested Use & Storage

All products sold are cosmetic grade; External Use Only; Cosmetic & Personal Care Formulations Only.
This product should be added to a formulation at the recommended usage rate.

 

Documents

SDS    
CoA-LOT: BN250330/CA
CoA-LOT: BN260728/CA
CoA-LOT: BN260509/CA
CoA-LOT: BN20230916/CA
CoA-LOT: BN221204/CA
CoA-LOT: BN240830/CA

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